Were carried out morphometric analysis of the ibroblasts ultrastructure of tenon capsule. Were examined
samples of the tenon capsule with the help of transmission electron microscopy with various types of
clinical refraction: 25 samples were examined with hyperopia, with low degree myopia – 1, medium degree
myopia – 6 specimens and high degree myopia – 15. It was found that with progressive myopia, the area of
the nucleus ibroblasts is larger than with hypermetropia (р ≤ 0.05), the extent of the karyoemma reaches
with progressive myopia 6.99 ± 0.199 nm, with hypermetropia – 5.40 ± 0.27 nm, (p ≤ 0.05). With the
progression of myopia, hyperplasia of the ibroblast nucleoli is registered, the amount is 0.17 ± 0.015 for
1 μm2 of the nucleus, for hypermetropia – 0.12 ± 0.006 for 1 μm2 of the nucleus, (p ≤ 0.05). With myopia progression, compared with hypermetropia, hyperplasia and hypertrophy of mitochondria (mitochondrial
count 2.05 ± 0.14 per 1 m 2 cells, outer membrane thickness 7.49 ± 0.06, thickness of crista 7.16 ± 0.17 nm,
maximum diameter of mitochondria 124.87 ± 7 , 18 nm, p ≤ 0.05). Lysosome hyperplasia of ibroblasts with
progressive myopia, 0.64 ± 0.08 per 1 m 2 of cells, (p ≤ 0.05) is recorded as compared with hypermetropia.
Thus, with increasing refraction, an increase in the number of ibroblast organoids is observed: nucleolus,
mitochondria, lysosomes, which indicates intracellular hyperplasia, as well as the core area, the length of
the maximal diameter of the karyolemma, the thickness of the outer membrane and the mitochondrial crises,
which are signs of hypertrophy.
Key words: ibroblasts, ultrastructural morphometry, hyperplasia, tenon capsule, refraction, progressive
myopia